This may be James Cluxton 1816-, who emmigrated from Ireland to New York on the “Australia” 1854.
(Some information in this tree from findagrave)
I cannot find this family in the 1860 census, but it may be this family. But there is a James Clarkson 1819-1881 who died in Philadelphia.
This may be
James Clarkson 1821- b Ireland = Elizabeth Clarkson 1822- b Ireland (1860: Catasauqua, Lehigh, PA. Rebecca M Kensy 1795- b Ireland was staying with them) Eugenia 1849 William 1851 Rebecca 1853 Mary 1855
According to this link, one daughter of James and Elizabeth was
Rebecca Clugston 1852.12.15-1876.5.1 b PA = Henry Booth
But the birth dates for Rebecca and William could not possibly be correct.
James Clugston 1819-1891.1.22 b Ireland = Elizabeth M McHenry 1830- b Ireland (All four parents born Ireland) (1880: Catasauqua, Lehigh, PA) William Clugston 1852.8.9-1924 = Hannah 1857-1924 m 1879 (1900: William said both parents born PA. No children) (1910: Allentown, Lehigh, PA) George Clugston 1860.6.25-1930 b PA = Margaret W Dunn m 1889.9.26 Carbon, Westmoreland, PA (1900: Hazelton, Luzerne, PA. Both Georges parents born Ireland) (1910: Philadelphia, PA) Mary D Clugston 1891- Russel A Clugston 1896- Nancy Clugston 1862-1913 b Catasauqua, PA = Robert McNabb b Ireland m 1887.9.27 James M Clugston 1865- b PA = Annie Morris 1864- m 1886.10.12 Catasauqua (Apparently changed surname to McHenry around 1888) (1891: Canada) Morris James Clugston 1888 b. Catasauqua Robert Clugston 1866.8 b PA = Sarah E Wyman 1863.1 b Delaware m 1895 (In 1900, 1910, 1920 Robert said his father born Scotland, mother born Ireland) (1900: Philadelphia, PA) (1910: Phildaelphia, PA) (1920: Phildaelphia, PA. Robert was widowed) (no children) Elizabeth Clugston 1868- b. Catasauqua = Franklin P Degroot m 1893.4.4 Catasaugua, Lehigh County, PA John Clugston 1872-1948 b PA = M Elizabeth Lee m 1897.9.21 Catasauqua (1900: Catasauqua, staying with parents John and Martha Lee) (1910: Phildaelphia, PA) (1930: Belmont, Middlesex, Massachusetts) (no children)